General Article Diet swap has dramatic effects on colon cancer risk for Americans and Africans

Topic Selected: Dietary Choices
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By Sam Wong

 

Scientists have found dramatic effects on risk factors for colon cancer when American and African volunteers swapped diets for just two weeks.

Western diets, high in protein and fat but low in fibre, are thought to raise colon cancer risk compared with African diets high in fibre and low in fat and protein. 

The new study, published in Nature Communications today, confirms that a high fibre diet can substantially reduce risk, and shows that bacteria living in the gut play an important role in this effect.

Colon cancer is the fourth commonest cause of death from cancer worldwide, accounting for over 600,000 deaths per year. Colon cancer rates are much higher in the western world than in Africa or the Far East, yet in the United States, African Americans shoulder the greatest burden of the disease.

To investigate the possible roles of diet and gut bacteria, an international team including scientists from the University of Pittsburgh and Imperial College London carried ou...

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