General Article UEA scientists make breakthrough for ‘next generation’ cancer treatment

Topic Selected: Cancer Book Volume: 433

Scientists at the University of East Anglia are a step closer to creating a new generation of light-activated cancer treatments.

The futuristic sounding treatment would work by switching on LED lights embedded close to a tumour, which would then activate biotherapeutic drugs.

These new treatments would be highly targeted and more effective than current state-of-the-art cancer immunotherapies.

New research published today reveals the science behind this innovative idea.

It shows how the UEA team have engineered antibody fragments - which not only ‘fuse’ with their target but are also light activated.

It means that in future, immunotherapy treatments could be engineered to attack tumours more precisely than ever before.

The principal scientist for this study, Dr Amit Sachdeva, from UEA’s School of Chemistry, said: ‘Current cancer treatments like chemotherapy kill cancer cells, but they can also damage healthy cells in your body such as blood and skin cells.

‘This means that they can c...

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